The MastAttack 107: The Layperson’s Guide to Understanding Mast Cell Diseases

Part One

1. What are mast cells?

2. What is mast cell disease?

Part Two

3. What causes mast cell disease?

4. Is mast cell disease heritable?

5. Can mast cell disease be cured?

Part Three

6. What symptoms does mast cell disease cause?

7. Why are skin and GI symptoms so common?

Part Four

8. Why are symptoms not the same for everyone?

9. Why do symptoms change over time?

Part Five

10. How is mast cell disease diagnosed?

11. What kind of doctor diagnoses mast cell disease? Can any doctor order these tests?

Part Six

12. What do these blood and urine tests look for?

Part Seven

13. What do these biopsies test for?

Part Eight

14. Are there special instructions for the tests to diagnose mast cell disease?

Part Nine

15. How is mast cell disease treated?

16. Do I have to take medication if I feel okay?

Part Ten

17. Does mast cell disease impact mood, anxiety, and depression?

18. Are medications for depression, anxiety or other psychiatric conditions used in mast cell patients?

Part Eleven

19. How do other conditions affect mast cell disease?

Part Twelve

20. Why do a lot of mast cell patients get intravenous (IV) fluids?

Part Thirteen

21. Why do people care so much about diagnostic criteria?

Part Fourteen

22. Is MCAS an early form of SM?

Part Fifteen

23. Is mast cell disease progressive?

Part Sixteen

24. What is degranulation?

Part Seventeen

25. How do I know what I will react to?

Part Eighteen

27. Can mast cell patients travel? Can they fly?

Part Nineteen

28. Why are so many mast cell patients anemic?

Part Twenty

29. Why do I swell up when I have a reaction? Where does the fluid come from and where does it go?

Part Twenty One

30. Why does my skin get red and itchy?

Part Twenty Two

31. Does mast cell disease cause cognitive issues?

Part Twenty Three

32. Is mast cell activation the same as mast cell activation syndrome?

Part Twenty Four

The questions I have already answered in other posts

Part Twenty Five

33. What is the difference between primary and secondary disorders? How do you know if your disorder is primary or secondary?

Part Twenty Six

34. What are the differences between the forms of systemic mastocytosis?

Part Twenty Seven

35. Why are there different sets of criteria for mast cell activation syndrome? What are the differences between them?

Part Twenty Eight

36. Is MCAS less serious than SM?

Part Twenty Nine

37. What is the difference between mast cell activation syndrome, mast cell activation disorder, and mast cell activation disease?

Part Thirty

38. What is the difference between the forms of cutaneous mastocytosis?

Part Thirty One

39. How are mast cell disease, Ehlers Danlos Syndrome and POTS connected? (Part One)

Part Thirty Two

39. How are mast cell disease, Ehlers Danlos Syndrome and POTS connected? (Part Two)

Part Thirty Three

40. What is mastocytosis of childhood? Is mast cell disease different from children than adults?

Part Thirty Four

41. Can my mast cell disease go away? Will it ever not be a problem?

Part Thirty Five

42. How is anaphylaxis related to mast cell disease? How do I know when to use my epipen?